Have you tried the basics like cleaning out your Temporary Internet Files, Cookies, and browsing history in IE?

Adobe Digital Editions software offers an engaging way to view and manage eBooks and other digital publications. Use it to download and purchase digital content, which can be read both online. Adobe digital editions 3.0 free download - Adobe Digital Editions, Adobe Digital Editions, Adobe Digital Editions, and many more programs. If you activated Adobe Digital Editions with an Adobe ID, which has already been used to activate Adobe Digital Editions on another computer, any DRM-protected Adobe eBooks downloaded before activating with the Adobe ID will no longer work. Download a single Adobe eBook on multiple computers and devices, each computer or device must be activated using the same Adobe ID. To activate Adobe Digital Editions using an Adobe ID: 1. Open Adobe Digital Editions. Library > Authorize Computer. The program you’ll need to open and read the file is Adobe Digital Editions. Here is how to make sure the file opens correctly: Once you have Adobe Digital Editions installed, it’s a good idea to make sure you select Adobe Digital Editions as the preferred program for these file types:.acsm and.epub.

Have you tried cleaning out your Temp folder, you can do it by typing %temp% in the Start Menu RUN box. This will open your Temp folder, there you can delete everything that Windows will allow you to do so.

You'll get this error message if you try to download an Adobe eBook on a computer or device. To activate Adobe Digital Editions using an Adobe ID: 1. Most major publishers use Adobe Digital Editions (ADE) to proof-read their books. Download this free eReader to experience your books in the most optimum format across PC, MAC, tablets or mobile devices. Use it to download and purchase digital content, which can be read both online and offline.

It may be necessary to show Both Hidden and System Files, and also to uncheck 'Hide known file types' in Control Panel/ Folder Options/ View, to navigate to the mentioned Temp location or access (and delete) all the hidden files in there.

You could also reset IE in case it is a problem with your browser or any running Add-ons.

How to use Reset Internet Explorer Settings (RIES)
http://support.microsoft.com/kb/923737#appliesto

Internet Explorer stops responding, stops working, or restarts [Guided help]:
http://support.microsoft.com/gp/pc_ie_intro:

Tips for solving problems with Internet Explorer
http://windowshelp.microsoft.com/Windows/en-US/Help/8038f9ac-9bf9-4809-8d75-fc42818d8af71033.mspx

Digital Editions Unable To Download Error Getting License

Can you download from 'Safe Mode with Networking'?

Advanced startup options (including safe mode)
http://windows.microsoft.com/en-US/windows7/Advanced-startup-options-including-safe-mode

How to troubleshoot a problem by performing a clean boot in Windows Vista or in Windows 7
http://support.microsoft.com/default.aspx/kb/929135

Have you tested the problem as a different user in case it is a profile problem?

System Restore might allow you to return to before March if you have sufficient restore points. It would also create an 'Undo' option in case it makes no difference.

How to repair the operating system and how to restore the operating system configuration to an earlier point in time in Windows Vista (or 7)
http://support.microsoft.com/kb/936212/#appliesto

How to use the System File Checker tool to troubleshoot missing or corrupted system files on Windows Vista or on Windows 7
http://support.microsoft.com/kb/929833

Adobe Digital Editions 2.0 is released and available for immediate download. This version includes major improvements for accessibility over Digital Editions 1.7, and is designed to provide greater access to both protected and unprotected electronic books in the EPUB format for Windows and Mac users.

Digital Editions 2.0 utilizes accessibility features on Windows and Mac OS to provide access for users who are blind or who have visual difficulties, including support for high contrast modes and support for resizing of book text. Digital Editions also offers keyboard support which is dramatically enhanced over version 1.7.

Screen reader users can use one of several tools to read books with Digital Editions. On Mac OSX VoiceOver support is provided, although one limitation at present is that book content can only be read one page at a time rather than as a continuous stream. On Windows, users can choose between JAWS, NVDA, and Window-Eyes. GW-Micro provides Window-Eyes support via an app – to get the app for Window-Eyes users should go to the Window-Eyes control panel, press ALT-A to get to the App Menu, and select AppGet. When the list of available apps is displayed, Digital Editions can be found in the “Program Enhancements” group.

Adobe Digital Editions Download

Adobe Digital Editions supports books protected by Adobe’s DRM (Digital Rights Management) solution. This allows users to access books available from libraries which use the Overdrive service, as well as those books purchased from vendors such as Barnes & Noble, Kobo, Waterstones, and other booksellers.

Unable To Download Files

Adobe Digital Editions 2.0 is free and available for download at http://www.adobe.com/products/digital-editions.html.